Comparison of 40% Glucose Solution and Autologous Blood Patch Pleurodesis for the Treatment of Postoperative Air Leak After Lung Resections: A Prospective Randomized Controlled Study
This prospective randomized trial compared intrapleural 40% glucose with autologous blood patch pleurodesis for postoperative air leak after anatomical lung resection. Glucose pleurodesis achieved higher air‑leak resolution rates and shorter hospital stay, with a similar safety profile and no increase in reoperation. Chest drain management was protocolized using -8 cmH2O, with pleurodesis initiated on postoperative day 3 for air leaks >20 mL/min and drain removal following sustained reduction to <20 mL/min for at least 8 hours. These findings suggest intrapleural glucose as an effective alternative strategy to expedite air leak closure and chest drain removal.
All Papers »