VALUE Trial: Phase 1 Safety and Feasibility Study of Same-Day Discharge After VATS Lung Resection

Lyndon C. Walsh, Merav Rokah, Joseph Seitlinger, Filippo Tommaso Gallina, Caroline Huynh, Morgan S. Gold, Avik Sengupta, Tia Nicholls-Wallace, Erin Cronin, Mehrnoush Dehghani, Roni Rayes, David Mulder, Christian Sirois, Mathieu Rousseau, Lorenzo Ferri, Jonathan Cools-Lartigue, Florin Costescu, Sara Najmeh, Jonathan D. Spicer  |  August 18, 2025

This phase 1 single-institution trial assessed the safety and feasibility of same-day discharge after video-assisted thoracoscopic surgery (VATS) lung resection. Nineteen patients underwent VATS lobectomy, segmentectomy, or wedge resection and were discharged home with a chest tube. Same-day discharge was achieved in 95% of cases, with a median chest tube duration of 2 days. One emergency department visit and two grade 2 prolonged air leaks occurred, with no serious adverse events. Quality-of-life outcomes were comparable to standard care, supporting the feasibility of same-day discharge in carefully selected patients.

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